About EnzySurge

EnzySurge, an Israeli company, was established by Prof. Amihay Freeman in the year 2001. Prof. Freeman, a Professor of Biotechnology and the incumbent Chair in Protein Nano-biotechnology at Tel Aviv University as well as being a Visiting Professor at University College London, has brought together an impressive team of field leaders in medical technologies such as Bio-chemical Engineering, Bio Chemistry, Nano Bio-technology, Micro Biology and Bio-Pharm – in order to specialize in producing proprietary innovative solutions for the global Chronic Wound Care market. The company’s products accelerate natural wound healing processes, and  are targeted at  outpatients in both  long term and homecare settings.

EnzySurge’s  flagship product, SilverStream® (branded as Qurion® or SealStream for some markets) is distributed in USA, India, Israel ,Korea ,Kenya, Nigeria ,Peru ,Belarus and other countries with more than 150,000 successfully treated patients worldwide, and this number is increasing daily. The use of SilverStream shortens substantially the wound healing duration while reducing suffer and pain.

SilverStream® is a novel, patented chronic wound management solution, combining a low concentration of silver ions, menthol, glycerol and a surfactant, dissolved in a hypertonic solution. The high concentration of the hygroscopic glycerol provides hydrogel effects.

SilverStream effectively and rapidly cleans, moisturizes and soothes chronic and hard-to-treat wounds

SilverStream’s® formulation effectively cleans, moisturizes and soothes chronic and hard to treat wounds. Its anti-bacterial property is more effective than products containing silver particles/nanoparticles, and provides four different unique mechanisms of action. One of its most advantageous functions is destroying biofilm. The special  synergistic combination of silver ions , menthol and surfactant enable the  reduction of the silver ions to a low concentration level - well below the cytotoxic threshold.

SilverStream® has been authorized  as a medical device by the US FDA, the CDSCO (Indian FDA), the Philippines FDA, the PPB (Kenya), the NAFDAC (Nigeria), the KFDA (South Korea), the DNM (El-Salvador), the DIGEMID (Peru),the MOH of Hong-Kong, Belarus  and the Israeli MOH for the treatment ulcers, stasis ulcers, diabetic foot ulcers, post-surgical wounds and first and second degree burns, cuts, abrasions and minor skin irritations.

SilverStream® is available in liquid and gel formulations and different bottle sizes.

The next product in the EnzySurge pipeline is EnzyStream™  - an enzymatic preparation, based on the enzyme Papain, for non-painful enzymatic debridement of chronic wounds, aimed at replacing painful scalpel debridement.
EnzyStream is currently in the clinical phase and is already proving  safety and efficacy in the  “first-in-man” studies (Phase 1/2a).


SilverStream effectively and rapidly cleans, moisturizes and soothes chronic and hard-to-treat wounds